The moulds can work with either PP, PE or HDPE, with no change of parts. This wide choice of materials, available worldwide, enables to pack a wide range of formulations, with low viscosity and with temperature ranging from 4°C to 30°C. BFS bottles have an optimal resistance to terminal sterilization as well as an . The wall thickness of the parison is easily controlled to produce container sfrom transparent to opaque, from very rigid to lightweight, and particularly self-collapsible to the extent of imitating flexible bags. Self-collapsible plastic bottles present all the advantages of flexible bags, plus they do not need an air vent during administration and are